Identifying Weekly Physical and Physiological Profiles in Professional Basketball Using Heart Rate Variability and Training Load Clustering

The Role of Gut Microbiota in Postmenopausal Women: Implications for Lipid Metabolism and Targeted Nutritional Interventions

Purpose of review: This review explores the complex interplay between menopause, estrogen decline, lipid metabolism, and gut microbiota alterations. It highlights the physiological and metabolic changes that predispose postmenopausal women to dyslipidemia and increased cardiovascular disease risk, with particular emphasis on the emerging role of the gut microbiota in modulating lipid homeostasis and inflammatory pathways. In addition, it examines the therapeutic potential of microbiota-target...

Alcohol and Substance Use After Bariatric Surgery: Nutritional Risks and Clinical Implications in Long-Term Postoperative Care

: Metabolic and bariatric surgery (MBS) has evolved into a highly effective neurohormonal intervention for severe obesity; however, it introduces unique long-term vulnerabilities, particularly regarding alcohol (AUD) and substance use disorders (SUD). This review synthesizes the epidemiological, pharmacokinetic, and neurobiological drivers of postoperative substance misuse. Procedures like Roux-en-Y gastric bypass (RYGB) radically alter ethanol metabolism, eliminating first-pass metabolism an...

Time Exposure and Fat Mass Reduction Drive Trimethylamine N-Oxide Modulation During a Very-Low-Energy Ketogenic Therapy (VLEKT) in Women with Obesity

: Background/Objectives: Trimethylamine N-oxide (TMAO) is a gut microbiota-derived metabolite increasingly recognized as a pro-atherogenic factor and a biomarker of cardiometabolic risk. Dietary patterns and adiposity are key modulators of circulating TMAO levels; however, evidence on the impact of very-low-energy ketogenic therapy (VLEKT) on TMAO metabolism, particularly in women with obesity, remains limited. This study aimed to investigate the effects of VLEKT on circulating TMAO concentra...